Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Depression
ADR ID BADD_A01208
ADR Hierarchy
19      Psychiatric disorders
19.15      Depressed mood disorders and disturbances
19.15.01      Depressive disorders
19.15.01.001      Depression
Description A disorder characterized by melancholic feelings of grief or unhappiness. [CTCAE] Depressive states usually of moderate intensity in contrast with major depression present in neurotic and psychotic disorders. [MeSH]
MedDRA Code 10012378
MeSH ID D003863; D003863; D003866
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Anxiety depression | Anxiety/depression | Anxious depression | Atypical depressive disorder | Depressed state | Depression | Depression aggravated | Depression functional | Depression mental | Depression NOS | Depression psychic | Depression worsened | Depressive disorder | Depressive disorder, not elsewhere classified | Depressive episode | Depressive illness | Depressive stupor | Exogenous depression | Mixed anxiety & depressive | Unipolar depression | Unipolar depressive illness | Depressive state | Acute depression | Chronic depression | Recurrent depressive disorder | Anxiodepressive syndrome | Depressions | Depressive Symptoms | Depressive Symptom | Symptom, Depressive | Symptoms, Depressive | Emotional Depression | Depression, Emotional | Depressions, Emotional | Emotional Depressions
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Glial fibrillary acidic proteinP14136Not Available
Protein c-FosP01100T28025
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00757Eliglustat0.021361%
BADD_D00759Eltrombopag--
BADD_D00762Elvitegravir--
BADD_D00765Empagliflozin--
BADD_D00766Emtricitabine--
BADD_D00767Enalapril maleate--
BADD_D00768Enalaprilat--
BADD_D00771Enfuvirtide--
BADD_D00773Entacapone--
BADD_D00774Entecavir--
BADD_D00775Enzalutamide--
BADD_D00786Eplerenone--
BADD_D00787Epoetin alfa--
BADD_D00788Epoprostenol--
BADD_D00790Eprosartan--
BADD_D00791Eprosartan mesylate--
BADD_D00793Equilin sulfate--
BADD_D00794Ergocalciferol--
BADD_D00798Eribulin--
BADD_D00799Eribulin mesylate--
BADD_D00800Erlotinib--
BADD_D00801Erlotinib hydrochloride--
BADD_D00803Ertapenem sodium--
BADD_D00804Erythromycin0.002182%
BADD_D00808Erythropoietin--
BADD_D00809Escitalopram0.006317%
BADD_D00810Escitalopram oxalate--
BADD_D00811Eslicarbazepine--
BADD_D00812Eslicarbazepine acetate--
BADD_D00813Esmolol--
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